Perinatal Pathology

Pathology of perinatal hypoxia.

At birth the newborn infant is required to make an abrupt adjustment to a new environment. The most immediate changes required to support extrauterine life are concerned with respiration and the circulation. The infant must be able to expand its lungs fully and at the same time the pulmonary circulation must be adequate for gaseous exchange to occur between the air spaces and the pulmonary capi...

Perinatal pathology in 2001.

Racial disparity in placental pathology in the collaborative perinatal project.

OBJECTIVE There is substantial disparity in perinatal outcomes between white and African-American women, but the underlying biological mechanisms are poorly understood. The placenta is the principal metabolic, respiratory, excretory, and endocrine organ of the fetus. We studied the association between maternal race and types and severity of placental pathology. METHODS Using data from the U.S...

Placental Pathology, Perinatal Death, Neonatal Outcome, and Neurological Development: A Systematic Review

BACKGROUND The placenta plays a crucial role during pregnancy for growth and development of the fetus. Less than optimal placental performance may result in morbidity or even mortality of both mother and fetus. Awareness among pediatricians, however, of the benefit of placental findings for neonatal care, is limited. OBJECTIVES To provide a systematic overview of the relation between placenta...

Effect of Fine Particulate Matter (PM2.5) on Rat Placenta Pathology and Perinatal Outcomes

BACKGROUND Fine particulate matter with aerodynamic diameters smaller than 2.5 μm (PM2.5) has been reported to cause adverse effects on human health. Evidence has shown the association between PM2.5 exposure and adverse perinatal outcomes, and the most common method is epidemiological investigation. We wished to investigate the impact of PM2.5 on placenta and prenatal outcomes and its related m...